Drusen accumulation in Bruch's membrane with age makes the membrane more hydrophobic or more hydrophilic?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $24.99Unlock all

Prepare for the NBEO Ocular Anatomy Posterior Segment and Cranial Nerves Test. Study with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

Multiple Choice

Drusen accumulation in Bruch's membrane with age makes the membrane more hydrophobic or more hydrophilic?

Explanation:
Drusen are lipid-rich extracellular deposits that accumulate between the RPE basement membrane and Bruch's membrane as we age. Because they contain a lot of neutral lipids and cholesterol esters, they raise the lipid content in the region, making it more hydrophobic. This shift toward lipids reduces water-friendly properties and hampers diffusion of nutrients and waste between the choriocapillaris and the RPE, contributing to age-related changes and AMD risk. So the membrane becomes more hydrophobic, not more hydrophilic or unchanged.

Drusen are lipid-rich extracellular deposits that accumulate between the RPE basement membrane and Bruch's membrane as we age. Because they contain a lot of neutral lipids and cholesterol esters, they raise the lipid content in the region, making it more hydrophobic. This shift toward lipids reduces water-friendly properties and hampers diffusion of nutrients and waste between the choriocapillaris and the RPE, contributing to age-related changes and AMD risk. So the membrane becomes more hydrophobic, not more hydrophilic or unchanged.

More Multiple Choice Questions
Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy