The inner blood-retinal barrier is formed by tight junctions between which cells?

Prepare for the NBEO Ocular Anatomy Posterior Segment and Cranial Nerves Test. Study with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

Multiple Choice

The inner blood-retinal barrier is formed by tight junctions between which cells?

Explanation:
The inner blood-retinal barrier is formed by tight junctions between retinal capillary endothelial cells. These endothelial tight junctions seal the paracellular space, regulating which substances move from the blood into the neural retina and keeping retinal neural activity stable. The outer barrier, in contrast, is created by tight junctions between the apical membranes of the retinal pigment epithelium. Photoreceptors are neurons and do not form the barrier, and while Müller cells support retinal structure and homeostasis, the primary tight-junction seal of the inner BRB resides in the endothelial cells lining the retinal capillaries.

The inner blood-retinal barrier is formed by tight junctions between retinal capillary endothelial cells. These endothelial tight junctions seal the paracellular space, regulating which substances move from the blood into the neural retina and keeping retinal neural activity stable. The outer barrier, in contrast, is created by tight junctions between the apical membranes of the retinal pigment epithelium. Photoreceptors are neurons and do not form the barrier, and while Müller cells support retinal structure and homeostasis, the primary tight-junction seal of the inner BRB resides in the endothelial cells lining the retinal capillaries.

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