Which layer of the retina contains the cell body of Muller Cells?

• A. Inner Nuclear Layer
• B. Inner Plexiform Layer
• C. Outer Nuclear Layer
• D. Ganglion Cell Layer

Answer: (A)

The cell bodies of Müller cells are located in the inner nuclear layer. Müller cells are the retinal glia that extend across the entire thickness of the retina, with their nuclei tucked in the inner nuclear layer and their long processes reaching through all layers to support and enwrap neurons. This arrangement allows their soma to sit within the INL while their fibers form the scaffolding that spans from the inner limiting membrane to the outer limiting membrane. In contrast, the outer nuclear layer houses photoreceptor cell bodies, and the ganglion cell layer contains ganglion cell bodies, while the inner and outer plexiform layers are mainly sites of synapses between neurons.